WHIPPLE'S DISEASE
WHIPPLE'S DISEASE Gram +ve organism : Trophreyma whipplei - Actinobacteria - slow doubling times - can't be cultured most common in males age group - 50 - 60yrs distal small intestine more affected than proximal small intestine whipple's disease is chronic multisystem disease - GIT + CNS + CVS + JOINTS HLA DR B1 13, HLA DQ B1 06 SYMPTOMS: GIT: Diarrhoea/weight loss anemia foul smelling stools abdomen distension + ascites abdomi...