HYPERTHYROIDISM
Hyperthyroidism is the condition that occur due to excessive production of thyroid hormones by the thyroid gland. CAUSES : A) PRIMARY HYPERTHYROIDISM Most common cause of PRIMARY HYPERTHYROIDISM is GRAVE'S DISEASE GRAVE'S DISEASE ↓ Have L.A.T.S - Ab (Long acting thyroid stimulating antibody) identical to TSH ↓ Resulting in INCREASE T4 , INCREASE T3 , DECREASE TSH B) SECONDARY HYPERTHYROIDISM Due to Pituitary adenoma ⇢ INCREASED TSH , INCREASED T3 , INCREASED T4 C) TOXIC NODULAR GOITER Frequent in areas of iodine deficiency Diagnosed by Thyroid scan using I - 123/I - 132 Warm nodule ⇒ Normal uptake Cold nodule ⇒ suggestive of malignancy Hot nodule ⇒ over active tissue D) JOD BASEDOW EFFECT : Seen with intake of iodized salt for long duration in iodine replete population. Has upgrade of [iodine trapping leading to increase production of T4/T3. E) THYROTOXICOSIS FACTITIA : It is Thyrotoxicosis occurring due to any other cause other than high salt intake. example: seen in...