HYPERMAGNESEMIA (electrolyte imbalance)
HYPERMAGNESEMIA It is an electrolyte disorder in which there is a high level of magnesium in the blood Death due to Asystole CAUSES: CKD - chronic kidney disease Eclampsia Mgso4 toxicity Antacids/Laxative abuse PATHOPHYSIOLOGY: Increase magnesium → inhibit PTH release -↓calcium→blood vessel relaxation neuromascilar excitability↓ - so reflexes decreased CLINICAL FEATURE: Shock - non responsive to vasopressors and IV fluid DTR↓ ,Respiratory rate↓,co2↓ urinary output↓ TREATMENT: Vigorous IV hydration Ca gluconate Hemodialysis