BERGER'S DISEASE
BERGER'S DISEASE It is also known as IgA Nephropathy first line of defence - IgA (Mucosal immunity) most common form of glomerulonephritis worldwide In berger's disease IgA increased with diffuse mesangial deposits - Capillaries - normal - golmerular filtration rate - normal - blood pressure - normal - microscopic Hematuria - If patient develops URTI (Upper respiratory tract infection) : IgA levels rise and over next 48 hours, microscopic hematuria is replaced by macroscopic / gross hematuria O/E - BP normal, no edema is noted WORKUP: >3RBC / HPF C3 normal in most cases TREATMENT: No consensus on optimal treatment