BERGER'S DISEASE

BERGER'S DISEASE


  • It is also known as IgA Nephropathy
  • first line of defence - IgA (Mucosal immunity)
  • most common form of glomerulonephritis worldwide
  • In berger's disease IgA increased with diffuse mesangial deposits




- Capillaries - normal
- golmerular filtration rate - normal
- blood pressure - normal
- microscopic Hematuria

- If patient develops URTI (Upper respiratory tract infection) : IgA levels rise and over next 48 hours,
microscopic hematuria is replaced by macroscopic / gross hematuria



O/E - BP normal, no edema is noted

WORKUP:
  • >3RBC / HPF
  • C3 normal in most cases
TREATMENT:
  • No consensus on optimal treatment


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